How I Use It
I use it to introduce topics to students, or as our main guidance throughout the day. You can embed videos and links to other sites as well. I have not practiced sharing the prezi with my students, but since there is a link, I would think you could link it in a virtual classroom. The Prezi is only as good as what you put in it, though. You need to have engaging, digitally diverse content in the Prezi, based on standards, to make it work well as an academic tool (hence the lower ratings in pedagogy and supports categories above). The program is pretty intuitive, so students can use it as a presenting tool as well.
It's a showier version of PowerPoint, and it holds student interest better than a power point. Because it's web-based, links to videos or other websites are much easier and more reliable than a power point. And there are some very cool effects you can incorporate. Designing a Prezi can be as simple or as complex as you would like it, and at the end of the day, even the simple ones look stunning. You definitely need time to play around with it, and see what other people are doing. You can get away with using the free educational version. In terms of setup, running the presentation once you've created it takes less than 5 minutes, but creating your presentations, especially a first, can be closer to fifteen minutes to an hour, depending on how you use technology and what you're putting in.