My Take
Do students learn that vaccinating healthy people keeps disease from spreading? Yes, but that is about it. The game does offer some brief information about vaccines, but mostly it is just a strategy game. I think it is good for all students as here is not much reading and the game promotes systems thinking. If you facilitate discussions about the game or maybe track data on game play, students could reflect on strategy and the importance containing disease.
How I Use It
Students could play individually or in groups of up to four players. They liked being able to play against each other, but some were frustrated by how quickly the disease spread. I would use this game for students who finished early or had some free time. It is a thinking games and teaches strategy, but I didn't see any real learning gains about disease or vaccination.