My Take
There's definitely an initial learning curve getting your network to handle the exploration along with getting student devices to join your Expedition. Also having portable devices and viewers and getting them set up will take a little why. That's why this won't likely be a regular activity, but is a great way to extend students learning or an exciting way to introduce a topic. They offer leveled questions with the Expeditions, so there is some differentiation.
How I Use It
It's a great resource for exploring the world beyond your classroom. It's currently geared mostly towards social studies and science based explorations with historical and famous world sites along with looking at ecological and biological diversity. It takes some set up, so it is not likely to be an regular activity. Usually I've used it as an introduction to a new unit.